2025 Biotech Startups
Order by: Company Name - Location
 10x Science |
CA - San Francisco | Protein Characterization Software |
| 1Elevan Bio |
IN - Fishers | Peptide Manufacturing |
| 2.0 Analytical Solutions |
NY - Sherburne | Chromatography Services |
| 3C Therapeutics |
BC - Vancouver | Degrader-Antibody Conjugate Platform |
| ABLi Therapeutics |
MA - Boston | Once-daily, potent, brain-penetrant, selective c-Abl kinase inhibitor; monoclonal antibody |
| Advita Ortho |
FL - Gainesville | Orthopedic Implants |
| Aerska |
Ireland - Dublin | RNAi, Delivery To Brain |
| Aethl Bio |
PA - Pittsburgh | Cellular Recovery |
| Aethox Therapeutics |
UK - London | Inhibitors |
| Aion Medicines |
CA - San Francisco | Ultra Long Lasting Medicines |
| Akatalyst Technologies |
India - Chennai | Quality Management System engineered specifically for pharmaceutical, biotech, and medtech organizations |
| Aletira Therapeutics |
MD - Baltimore | Gene therapies that use alternative splicing |
| ALP Bio |
Switzerland - Schlieren | Antibody Immunogenicity Assessment |
| Altagenics |
CA - Los Angeles | GigaAssay-derived therapies |
| Alturos Therapeutics |
Netherlands - Tilburg | Neurology Small Molecules |
| Amani Therapeutics |
- | Combination product |
| Anavatos Bio |
WA - Seattle | Integrated Platform for Biologics Production |
| Angstrom Innovation |
CA - Berkeley | Sequencing |
| Antares Therapeutics |
CA - South SF | Small Molecule Technologies |
| Antares Therapeutics |
MA - Boston | Small Molecule Technologies |
| Artis BioSolutions |
CA - San Diego | CDMO - Gene Therapy, Biologics |
| Ashlins Pharmaceuticals |
- | Rare Disease Therapy |
| Ategenos Pharmaceuticals |
MA - Cambridge | Connected drug delivery and non-adherence monitoring |
| Aurora Therapeutics |
MA - Cambridge | Personalized Gene Editing |
| Avitia |
QC - Montreal | AI Cancer Diagnostics |
| Azkarra Therapeutics |
CA - South SF | Small molecule modulators of DNA damage response (DDR) pathways |
| Beeline Medicines |
MA - Boston | Small Molecules, Antibodies, Fusion Proteins |
| BioArk Technologies |
MD - Rockville | CRO specializing in gene editing and delivery |
| BioClec |
Italy - Milan | Novel therapies targeting microglia |
| Bion Labs |
Brazil - Sao Paulo | Peptide-only CMC governance consultancy for early-stage biotech approaching CDMO engagement. |
| Bionyra Pharma |
France - Paris | Mono and multispecific antibodies |
| BioPrompt |
India - Bangalore | Drug Discovery Consulting |
| BioRegenEx |
TX - Houston | MSC-derived Exosomes |
| Blank Bio |
CA - San Francisco | RNA intelligence for precision oncology |
| Boltz |
UK - London | AI Drug Discovery Platform |
| Branch Therapeutics |
AZ - Tucson | Oral dual-pathway inhibitors that prevent cancer recurrence |
| Brano Therapeutics |
Singapore - Singapore | Heart Failure Treatments |
| BTLabs |
CA - San Francisco | Peptide, Oligo, Enzyme Testing |
| Callio Therapeutics |
WA - Seattle | Multi-payload antibody-drug conjugate technology |
| Carolina Molecular |
NC - Morrisville | Molecular Testing Services |
| Celea Therapeutics |
MA - Boston | Lung Disease Therapy |
| Chrysalis |
MA - Burlington | GMP Space |
| Chrysalis |
MA - Waltham | GMP Space |
| Chrysalis |
NC - Morrisville | GMP Space |
| Chrysoli Consulting |
FL - Orlando | Market Access Consulting |
| Cirena |
CO - Boulder | RNA Synthesis |
| Clinical Finance Consulting |
MN - Saint Paul | Financial Consulting |
| Coultreon Biopharma |
Belgium - Heverlee | SIK Inhibitors |
| Crystal NAX |
NJ - Cranbury | R&D services for RNA therapeutics - nucleic acid design, synthesis, and delivery using lipid nanoparticles |
| Crystalys Therapeutics |
CA - San Diego | Oral, URAT1 inhibitor for gout |
| Cynaptec Pharmaceuticals |
BC - Vancouver | Psychedelics |
| Dayra Therapeutics |
ON - Toronto | Oral Macrocyclic Peptides |
| Diploid Genomics |
CA - San Diego | Diploid genome sequencing for AI Diagnostics |
 |
CA - Hayward | DuneX Biosciences | Yeast display CRO delivering antibody/VHH discovery, affinity maturation, and protein evolution from drug-like scFv and nanobody libraries. |
| Electrome |
CA - Los Angeles | AI for Bioelectric Therapy |
| Elevara Medicines |
UK - London | Small Molecule for RA |
| Elvinix |
UK - Cambridge | Functional Diabetes (1) Cure |
| Endurance Bio |
CA - San Francisco | Oral Small Molecules |
| Enlila |
Turkey - Istanbul | Antibodies for obesity and other metabolic diseases |
| Enodia Therapeutics |
France - Paris | Treatment for cancer, inflammatory diseases, and viral infections |
| EpiFrontier Therapeutics |
Japan - Kyoto | Small Molecule Inhibitors |
| Epitome Therapeutics |
Austria - Vienna | Epigenome editing |
| Epitype |
Germany - Jena | Molecular cancer diagnostics |
| Etienna Bio |
KS - Overland Park | Autologous Breast Implants |
| Evinco Therapeutics |
Australia - | NK cell-derived extracellular vesicles for Alzheimer's and neuroimmune diseases |
| Ex-Amplify Therapeutics |
CA - San Diego | Migraine Treatment |
| Excalipoint Therapeutics |
China - Shanghai | Cell Therapy, Antibodies |
| Excellergy |
CA - Palo Alto | Allergic Effector Cell Response Inhibitors |
| Expedition Medicines |
MA - Cambridge | Generative Design of Small Molecules |
| FireGate Biotech |
DC - Washington | Immune Modulation |
| Fog City Bio |
CA - San Carlos | Rapid ELISA Optimization |
| Fortitude Biomedicines |
MA - Waltham | Bispecific Antibody |
| Genyro |
CA - San Francisco | DNA Construction Technology |
| Gestala |
China - Dengdu | Brain-computer Interfaces |
| GlioCart |
Switzerland - Allschwil | CAR T Glioblastoma Therapy |
| H3Tech |
GA - Atlanta | Healthcare Software Development |
| Hillstar Bio |
MA - Boston | Next-Gen Immunotherapies |
| Houdini Bio |
UK - London | Gene Therapies |
| Human Continuum |
FL - Jupiter | Platelet-derived Exosomes |
| iDEL Therapeutics |
Germany - Dortmund | Synthetic Shuttle for Cytosolic Drug Delivery |
| ImmunoSig |
UK - Manchester | Peptide and protein microarray immunoprofiling |
| Immuthera |
Poland - Gdansk | T Reg Cell Therapies |
| Innosphera Pharma |
QC - Montreal | Orally-active Molecule |
| InnovApproach Consulting |
Australia - Melbourne | Boutique consulting firm specializing in the qualification and use of New Approach Methodologies (NAMs) including the FDA ISTAND Program |
| Intent Biologics |
MN - Rochester | Regenerative Exosome Biologics |
| InterAct Therapeutics |
TX - Dallas | Gene Therapy |
| iRiva Medical |
MN - Minneapolis | Next generation neuromodulation technology |
| Jocasta Neuroscience |
AZ - Scottsdale | Protein therapeutic targeting cognitive decline in neurodegenerative diseases |
| Juniper Biosciences |
NJ - Bridgewater | Radiopharmaceuticals |
| Kahimmune Therapeutics |
France - Avignon | Cancer Vaccines |
| Keenova |
Ireland - Dublin | Small Molecules |
| Keenova |
MO - Hazelwood | Small Molecules |
| Keenova |
NJ - Bridgewater | Small Molecules |
| Keenova |
PA - Malvern | Small Molecules |
| Kinvard Bio |
NC - Raleigh | Antibiotics |
| Klona Biotech |
UK - London | Printed Implants |
| Lila Sciences |
MA - Cambridge | Scientific superintelligence platform and fully autonomous labs |
| LIR Life Sciences |
BC - Vancouver | GLP-1 Drug Delivery |
| Lokahi Therapeutics |
CA - La Jolla | |
| mAIbe |
Italy - Rome | Monoclonal Antibodies for Viruses |
| Manakin Bio |
- | AI Pathogen Detection |
| Manaolana Oncology |
- | Monoclonal Antibodies |
| MantaBio |
MA - Beverly | Real-time PCR System |
| Maxymune Therapeutics |
CA - Los Altos | Small Molecule Inhibitors |
| Mendra |
CA - San Francisco | AI Drug Discovery Rare Disease |
| Metri Bio |
MA - Boston | Endometriosis Therapies |
| Minaris |
PA - Philadelphia | CGT CDMO and Biosafety Testing Lab |
| MiniMed |
CA - Northridge | Diabetes Management |
| Minnesota Medical Technologies |
MN - Stewartville | Continence care products |
| Mondego Bio |
Portugal - Cantanhede | Cancer Immunotherapies |
| MultiValent Biotherapies |
CA - Los Altos | Prostate Cancer Treatment |
| MygoGenesis |
MD - Germantown | Autologous Totipotent Cells |
| NanoNewron |
NJ - Union | Carrying Biologics Across the Blood-Brain Barrier |
| NAYA Therapeutics |
FL - Miami | Antibody Therapy for Oncology |
| NEOK Bio |
CA - Palo Alto | Novel antibody drug conjugates (ADCs) for improving outcomes for cancer patients |
| Nerai Biosciences |
Switzerland - Zurich | Genome Editing |
| Newleos |
MA - Boston | Anxiety and substance abuse disorder treatments |
| NexCulture |
Japan - Uruma | Incubator Monitoring |
| Noara Therapeutics |
MA - Watertown | Therapeutic RNAs |
| Notiva Labs |
TX - Austin | SOPs and process documentation |
| OpZira |
PA - Middletown | Detection and Monitoring of Ocular Disease |
| Ospri |
TX - McKinney | Multiplex molecular assays |
| OTR Therapeutics |
China - Shanghai | Treatments for immunology & inflammation, oncology |
| Outpost Bio |
UK - London | Human Microbiology Models |
| Ovo Labs |
UK - Cambridge | IVF Egg Quality |
| Pahr Therapeutics |
MA - Boston | PAH Treatments |
| Par Health |
MO - St. Louis | Generics |
| Peapod Bio |
IL - Chicago | Assay development, HTS, and hit-to-lead, small molecules and peptides, proprietary MS technology |
| Pictor |
CA - Carlsbad | Next-gen targeted proteomics. Faster, scalable, and affordable testing |
| Plasmidsaurus |
CA - South SF | Genome Sequencing Services |
| Poplar Therapeutics |
MA - Boston | anti-IgE therapy |
| Precision CellSystems |
CA - Livermore | Tissue Processing Platform |
| PridCor Therapeutics |
AL - Tuscaloosa | Therapies designed to address the root causes of post-viral syndromes and chronic conditions |
| Prolium Bioscience |
NY - New York | Small Molecule for Autoimmune Disease |
| ProTgen |
- Virtual | Targeted Notch activators to reconstitute the adaptive immune system |
| Protuoso Biosciences |
CA - San Carlos | AI-driven Protein Engineering |
| PsiThera |
MA - Watertown | Oral Small Molecules |
| Pursuit Scientific |
NJ - Cape May | Direct to scientist US manufactured precision LC, GC, MS chromatography vials for analytical science |
| Quetzal Therapeutics |
IL - Chicago | Oral arsenic trioxide therapy |
| R1 Therapeutics |
CA - San Francisco | Small Molecule Targeting Hyperphosphatemia |
| Radical Numerics |
CA - San Francisco | Generative genomics |
| Rare Therapeutics |
PA - Philadelphia | Gene Therapies for Ultra Rare Diseases |
| Reprogram Biosciences |
CA - San Carlos | Reprogramming cancer cells |
| Resolve M Therapeutics |
MA - Boston | Pro-resolution platform for target ID, validation, and drug discovery in inflammatory diseases |
| Rezon Bio |
Poland - Duchnice | Analytics, development, GMP manufacturing, and formulation |
| Rhapsogen |
MA - Cambridge | Autoimmune Treatment |
| Rinascera Therapeutics |
MA - Boston | Small Molecule, Biologics |
| RxMP Therapeutics |
WA - Seattle | Therapies to prevent and treat hemorrhage and excessive bleeding |
| Scripta Therapeutics |
UK - Oxford | AI, imaging, and patient-derived models for drug discovery |
| Sentinel BioTherapeutics |
TX - Houston | Localized Immunotherapies |
| Shenandoah Therapeutics |
CA - South SF | Cancer Driver Therapies |
| Signadori Bio |
France - Paris | Cell Therapy Platform |
| Skape Bio |
Denmark - Copenhagen | GPCR Drug Discovery with AI -Designed Biologics |
| Skeletalis |
MA - Boston | Osteoporosis Treatment |
| Solid IO |
Finland - Helsinki | Organ-on-a-chip for Cancer Decisions |
| Sub-Q Bionics |
Israel - Tel Aviv | Lymphedema Implant |
| Swan EndoSurgical |
MA - Boston | Endoluminal Surgical Robotic Solutions |
| Sycomia |
France - Rosenau | Bioinformatics Services |
| SylamoreBio |
AR - Jonesboro | RTB-Lectin-Based Delivery Platform |
| Symbiotic.blue |
UK - London | AI Drug Discovery |
| Synaptra Bio |
Australia - Sydney | Neurodegenerative Therapies |
| Syndeio Biosciences |
IN - Indianapolis | Brain Health Treatments |
| Syremis Therapeutics |
Israel - Tel Aviv | Best-in-Class Medicines for Mental Health Conditions |
| Tasman Therapeutics |
CA - San Francisco | Oral Extended Release Ketamine |
| Therna Biosciences |
CA - San Francisco | RNA Therapies |
| Tidewave Bio |
CA - Los Angeles | antigen-presenting cell therapy platform |
| Tiger Wound Care |
PA - Conshohocken | Wound Care, Pain Management |
| Timberlyne Therapeutics |
NY - New York | Monoclonal Antibody |
| Transneural Therapeutics |
WA - Issaquah | Non-hallucinogenic neuroplastogens |
| TriasBio |
CA - San Francisco | Computational RNA Engine |
| Uncover Therapeutics |
UK - Cambridge | Immuno-oncology |
| Until Labs |
CA - San Francisco | Reversible Cryopreservation for Organ Procurement |
| USIL Therapeutics |
Luxembourg - Hollerich | Radiological Protection |
| VB Spine |
NJ - Allendale | Spinal Implants |
| VB Spine |
VA - Leesburg | Spinal Implants |
| Vector Science & Therapeutics |
WI - Mequon | Biomechanical devices and active localized drug delivery platforms |
| Ventuno Biotech |
France - Lyon | Immunotherapies |
| Veritas Aortic Solutions |
CA - Costa Mesa | Transcatheter Valved Aortic Root Conduit |
| Vibraint |
Denmark - Frederiksberg | Virtual brain technologies |
| Vivacta Bio |
China - Shanghai | Next-generation in vivo CAR-T therapies for cancer and autoimmune diseases |
| Vivatides Therapeutics |
MA - Woburn | RNA Therapeutics |
| Vixen Bio |
Belgium - Gent | Antibody work |
| Wield Therapeutics |
CA - San Mateo | Antibody Therapeutics |
| YD Bio |
WA - Bothell | Cancer Diagnostics, Services |
| Zeon Systems |
CA - San Francisco | Lab Automation |
| ZymagenX |
CA - Newport Beach | Recombinant proteases |